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Smart Technology. Customizable Therapy. Based on Proven Results.
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Prevent
Normal Mode
Prevent seizures with long-term effectiveness2
Therapy delivered at regular intervals all day, everyday1
Respond
AutoStim Mode
Automatically attempts to stop or shorten a seizure, improve recovery3
Automatic delivery of therapy activated by a proven seizure biomarker4
On-Demand
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Attempts to stop or shorten a seizure, improve recovery3
Manually activated delivery of acute therapy1
How VNS Therapy with responsive stimulation works
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*Single patient example from clinical trial. Individual results may vary.
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What do patients say are the benefits of VNS Therapy?
The benefits of VNS Therapy are seen early—often within 3 months7—and continue to improve out to 10 years8
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Lower Risk of SUDEP for Patients with VNS Therapy over Time9,10
Multiple long-term studies support:
SUDEP risk significantly decreases during long-term follow-up of patients receiving VNS Therapy海外加速器YouTube
*Sudden Unexpected Death in Epilepsy
SEIZURE COUNT
Fewer Seizures
Sustained Control
Improves over Time2,8
Multiple long-term studies support:
≥ 90% seizure reduction achieved in 1 out of 4 patients11,12
≥ 50% seizure reduction achieved in half to two-thirds of patients求上油管的加速器
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Shorter Seizures
Reduced Severity
Improved Recovery2
Multiple long-term studies support:
Significant reduction in seizure duration, severity, and improved post-ictal recovery in children and adults7,16
QUALITY OF LIFE
Improved Mood, Memory, and Alertness2
3 out of 4 patients report a net improvement in QoL17
Multiple long term studies support:
Significant reduction in status epilepticus18, ER visits, and hospitalizations by up to 50%18,19
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No drug interactions or drug-related toxic central nervous system side effects2
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SUDEP
Long-Term Surveillance of SUDEP in Drug-Resistant Epilepsy Patients Treated with VNS Therapy
Ryvlin P, et al. Epilepsia. 2018; 59:562–572.
Download
AutoStim
A prospective, multicenter study of cardiac-based seizure detection to activate vagus nerve stimulation
Boon P, et al. Seizure. 2015; 32: 52-61.
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Automatic Vagus Nerve Stimulation Triggered by Ictal Tachycardia: Clinical Outcomes and Device Performance—The U.S. E‐37 Trial
Fisher RS, et al. Neuromodulation. 2016; 19: 188-195.
Download
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Quality-of-life metrics with vagus nerve stimulation for epilepsy from provider survey data
Englot DJ, et al. Epilepsy & Behavior. 2017; 66:4–9.
Download
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After VNS Therapy... I stepped out of the darkness and into the light.
- Starr, on VNS Therapy since 2003
Before VNS therapy, I was having multiple seizures a day. After VNS therapy, the last seizure I’ve had was a few months ago.
- Aaron, on VNS Therapy since 2008
Her quality of life has—it’s just changed. It’s just miraculous. It’s been a lifesaver.
- Nicole, Vivien's Mother
Vivien, on VNS Therapy since 2015
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Browse Resources Contact Us
1. VNS Therapy Physician’s Manual, LivaNova, Inc. Houston, TX. 2. Epilepsy Patient's Manual for Vagus Nerve Stimulation, LivaNova, Inc., Houston, TX. 3. Fisher RS, et al. Neuromodulation. 2016; 19: 188‐195. 4. Eggleston KS, et al. Seizure 2014;23(7):501. 5. Data on File, LivaNova, Inc., Houston, TX. 6. Adapted from Boon P, et al. Seizure. 2015; 32: 52‐61. 7. Boon P, et al. Seizure. 2015; 32: 52‐61. 8. Elliott RE, et al. Epilepsy Behav 2011;20(3):478‐483. 9. Ryvlin P, et al. Epilepsia. 2018; 59:562–572. 10. Annegers JF, et al. Epilepsia 2000;41:549‐553. 11. Elliott RE, et al. Epilepsy Behav 2011;20(1):57‐63. 12. Kawai K, et al. Epileptic Disord 2017;19(3):1‐12. 13. Labar DR. Seizure 2004;13:392‐8. 14. Vonck K, et al. J Clin Neurophysiol 2004;21:283‐9 15. De Herdt V, et al. Eur J Paediatr Neurol 2007;11:261‐9. 16. Orosz I, et al. Epilepsia. 2014; 55(10):1576‐1584. 17. Englot DJ, et al. Epilepsy & Behavior. 2017; 66:4–9. 18. Helmers SL, et al. Epilepsy Behav. 2011 Oct;22(2):370‐5. 19. Bernstein A, et al. Epilepsy Behav 2007;10:134‐137. 20. Ben‐Menachem E J. Clin Neurophysiol 2001 Sep;18(5):415‐418. 21. Morris GL 3rd, et al. Neurology 1999 Nov 10;53(8):1731‐1735.